I went to Windows 10 about a week ago now and all seems good, though I did notice a few dropouts on one old project, which seemed to be cured when I turned off ASIO guard, which I have left disabled. I also tried the registry fix mentioned here, and I no longer have any occasional ASIO meter red light peaks (which I have always had on Windows7 too)
Computer specs are as per my sig below, latest Cubase Pro8 version, I’m using Halion 5 a lot, Izotope Nectar2 and Alloy2 often used on inserts, and usually Izotope 6 on stereo master out. UVI workstation instrument also working well. All seem stable and problem free. No midi problems found at all.
I haven’t tried video yet so cannot comment on that.
UPDATE: Have now loaded a couple of video projects (Quicktime 7.7.2 currently installed) running without any apparent problems.