WL 8.5.20 does'nt remember program settings...

Lately WL 8.5.20 (WIN7) hangs on an old state, always opening an old session on startup with it’s preset. New files (smth. like open last project/file/preset) and presets, program settings are ingnored - it always returns to it’s old state. When i close this old file in WL i get an error message (cannot save file…).
Does anyone know what to do ?

This is like if WaveLab can’t write to its setting path. Please show a screenshot of the 1st page of the general preference dialog.