A couple questions: Crash when switching apps, and trashing preferences

You don’t need to look any further. Yes it does.
You even gave us a major clue :

If you did that too fast without waiting for the driver to load/unload, then all it did was corrupting the channels data in Cubase, resetting the devices in Windows and creating duplicates.
In short it fu*ked up everything, especially if the sample rate wasn’t the same in windows.

Please follow these steps if you don’t want such a thing to happen again.