After almost 2 years of drop outs, I finally updated my motherboard and processor and am pleased to say I did not have to tweak almost anything to get good performance on my UR824.
Before: X99 board with 6 core 5820K 32 gig memory, Nvidia graphics. drop outs almost constantly, disabled Hyperthreading, C states, power always on, finally helped by Nvidia power tweak fix and v 1.10.0 driver. Still occasionally temperamental and ran hot.
After. Z370 board with 6 core 8700K, same memory as above, same graphics. v1.10.0 driver, power set to always on. No problems whatsoever. Even OCed the chip to 4.8 per core and its sweet as can be, eats VSTi’s for breakfast… 
Hard to admit but somewhere along the line my last build did just not work for audio, I should have been a beast but between the UR driver problems and the hardware it was a just a disaster.
Different matter this time… Interface working perfectly and at very low latencys, finally…