Ur22c audio interruption due usb

Maybe this helps… some users reported that some of the settings helped. Make sure to check it out:
It seems that the Yamaha driver can’t communicate right sometimes when :

  1. Internal windows audio driver is disabled in bios
  2. When using MBR file system
  3. When using other OS Type setting in bios instead of Windows UEFI mode
    On new systems this option is sometimes automatic on (Other OS)
  4. When using XHCI mode
  5. When Intel Turbo Boost Technology is enabled

Fix: Audio interruption due to USB error is detected. (Windows) - Cubase - Steinberg Forums